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Mitochondrial Dysfunction Is a Driver of SP-2509 Drug Resistance in Ewing Sarcoma.
Tokarsky EJ, Crow JC, Guenther LM, Sherman J, Taslim C, Alexe G, Pishas KI, Rask G, Justis BS, Kasumova A, Stegmaier K, Lessnick SL, Theisen ER. Tokarsky EJ, et al. Among authors: crow jc. Mol Cancer Res. 2022 Jul 6;20(7):1035-1046. doi: 10.1158/1541-7786.MCR-22-0027. Mol Cancer Res. 2022. PMID: 35298000 Free PMC article.
The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma.
Boone MA, Taslim C, Crow JC, Selich-Anderson J, Byrum AK, Showpnil IA, Sunkel BD, Wang M, Stanton BZ, Theisen ER, Lessnick SL. Boone MA, et al. Among authors: crow jc. Oncogene. 2021 Jul;40(29):4759-4769. doi: 10.1038/s41388-021-01876-5. Epub 2021 Jun 18. Oncogene. 2021. PMID: 34145397 Free PMC article.